GeroScience - Jan 18, 2025
DNA methylation clocks struggle to distinguish inflammaging from healthy aging, but feature rectification improves coherence and enhances detection of inflammaging
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Your full-body aging profile, decoded
Our proprietary 460-biomarker panel delivers the most comprehensive aging profile available today.
Clinically validated. Head-to-head tested.
See how The SystemAge™ stacks up in direct comparisons against traditional biological age clocks— and why doctors are standing behind it.
Read Our Case Study →| SystemAge™ | DunedinPACE | PhenoAge | |
|---|---|---|---|
| Accuracy | 0.99 | 0.58 | 0.57 |
| Confidence (MMC) | 0.97 | 0.16 | 0.14 |
| Specificity (TNR) | 0.983 | 0.584 | 0.573 |
| Sensitivity | 0.994 | 0.576 | 0.568 |
| Negative Predictive Value (NPV) | 0.986 | 0.537 | 0.568 |
| F1-score | 0.993 | 0.586 | 0.571 |
Stop waiting for symptoms to start
Aging is the root cause of most chronic illness. SystemAge is the first and only clinically validated test that detects early biological risks—before you feel a thing.
Your body speaks before disease strikes. We help you listen.
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Turning health data into real decisions
Personalized health insights. Clinically backed. Built for your body.
Our proprietary Intelligence Engine™ analyzes your biological age data to deliver tailored recommendations—grounded in science, designed for change.
Dive into the scientific foundation of our tests through decades of rigorous research and peer-reviewed studies published in leading journals.
Dive into the scientific foundation of our tests through decades of rigorous research and peer-reviewed studies published in leading journals.
DNA methylation clocks struggle to distinguish inflammaging from healthy aging, but feature rectification improves coherence and enhances detection of inflammaging
The dominance of old blood, and age-related increase in protein production and noise
DNA methylation clocks struggle to distinguish inflammaging from healthy aging
DNA methylation clocks struggle to distinguish inflammaging from healthy aging
A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
We're honored to be the choice of the medical pioneers who use our insights to transform lives, every day.
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Pioneer in Genomic Medicine, Author & Medical Professor. “With traditional medicine falling short, there's a growing demand for personalized data to prevent illness.”

Specialist in Longevity Medicine

Founder of Churchill Center, Specialist of Integrated Healthcare

Executive chairman of the X Prize Foundation. “We're the first generation with the power to understand and slow aging, extend human healthspan. Generation Lab is at the forefront of that science.”

Pioneer in Genomic Medicine, Author & Medical Professor. “With traditional medicine falling short, there's a growing demand for personalized data to prevent illness.”

Specialist in Longevity Medicine

Founder of Churchill Center, Specialist of Integrated Healthcare

Executive chairman of the X Prize Foundation. “We're the first generation with the power to understand and slow aging, extend human healthspan. Generation Lab is at the forefront of that science.”

Founder of Boulder Longevity Institute

The Robert Winthrop Professor of Genetics at Harvard Medical School. "The team is taking cutting edge research straight out of the lab and applying it to a pressing issue: identifying disease much earlier than ever before possible using genetic markers. It's a pivotal moment in epigenetics and I'm excited to see what unfolds

Physician at Alhambra Hospital Medical Center & Garfield Medical Center

Owner & CEO of Institute of Regenerative Health

Founder of Boulder Longevity Institute

The Robert Winthrop Professor of Genetics at Harvard Medical School. "The team is taking cutting edge research straight out of the lab and applying it to a pressing issue: identifying disease much earlier than ever before possible using genetic markers. It's a pivotal moment in epigenetics and I'm excited to see what unfolds

Physician at Alhambra Hospital Medical Center & Garfield Medical Center

Owner & CEO of Institute of Regenerative Health

Regenerative Medicine Doctor, CEO & Founder of Eterna Health. “We are now ready for healthcare 3.0 focusing on prevention. SystemAge is the tool that I trust.”

Regenerative Medicine Doctor, CEO & Founder of Eterna Health

Certified Health Coach & Host of Wellness Is Life Podcast

Founder of Slight Motion PT

Regenerative Medicine Doctor, CEO & Founder of Eterna Health. “We are now ready for healthcare 3.0 focusing on prevention. SystemAge is the tool that I trust.”

Regenerative Medicine Doctor, CEO & Founder of Eterna Health

Certified Health Coach & Host of Wellness Is Life Podcast

Founder of Slight Motion PT
SystemAge™ by Generation Lab operates to ISO/IEC 17025 standards, ensuring reliable, high-quality analysis. The platform follows GDPR- and HIPAA-aligned data protection principles and can be delivered as a white-label solution for scalable preventive health and longevity programs.