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Advanced Proteomics
A molecular view of your protein profile.
Non-invasive cheek swab, collected at home or in a clinic.
- Buccal swabNon-invasive collection
- 7,496Protein groups in the curated library
- 508 proteinsUsed in the ProteoAge model
Overview
What the report includes
A non-invasive proteomic test that analyses proteins from a cheek swab and translates them into ageing-related estimates, functional pathway scores and personalised lifestyle insights.
Proteins carry out almost every process in the body, and their expression shifts with age, diet, training and stress. Protein profiles complement genetics, epigenetics, metabolomics and routine clinical biomarkers. Each biological layer provides different information.
- 01
Ageing profile
- ProteoAge
- Index of Aging
- Model-derived scores mapped to the Hallmarks of Aging framework
- 02
Functional protein insights
- Cellular energy
- Metabolic regulation
- Inflammatory response
- Nutrient handling
- Connective tissue
- Oral health
- 03
Lifestyle and recommendations
- Nutrition profile
- Sport profile
- Personalised food, activity and supplement suggestions for professional review
What is measured
Inside your proteomic report
The report brings ageing, nutrition, sport and functional protein insights together in a visual dashboard, with detailed explanations and personalised recommendations.
Ageing
ProteoAge and the Index of Aging.Nutrition
A profile of nutrient-related protein pathways.Sport
Activity and recovery-related insights.Hallmarks
Model-derived ageing pathway contributions.Biomarkers
Functional protein profiles and status categories.Recommendations
Personalised food, activity and supplement suggestions, for professional review.
Inside the report
What the report shows
Five connected views
- Excellent 15
- Good 1
- Optimisable 5
ProteoAge and the Index of Aging
−6.2years, model-derived difference from calendar age
Index of Aging 0.8 · Excellent
Hallmarks of Aging: top 3 and bottom 3
Functional protein profiles
- Nutrient profilesVitamin A turnoverThe cycle of vitamin AExcellent
- Vitamin E turnoverVitamin E usage in the bodyExcellent
- Vitamin D turnoverUtilisation for bone, immune function and metabolismExcellent
- Zinc turnoverZinc handling for immune function and healingOptimisable
- Structural & organ healthRenal efficiencyRemoving waste productsExcellent
- Connective tissue healthTissue resilienceExcellent
- Inflammatory responseInflammatory response (CRP-related)Acute inflammatory activityExcellent
What you get
From protein data to a plan you can act on
For the patient
- ProteoAge, a model-derived protein age compared with your calendar age
- Your Index of Aging and Hallmarks of Aging profile
- Nutrition and sport profiles
- Functional protein profiles with clear status categories
- Food, activity and supplement suggestions to review with a professional
For the clinician
- A functional layer next to genetics, epigenetics, metabolomics and routine biomarkers
- Hallmark-level contributions to help prioritise follow-up
- A proteomic baseline for exploring change over time
- Non-invasive collection, at home or in clinic
- Reported test-retest repeatability for relative biological age
How it works
From sample to insight
- 01
Collect
A cheek swab, taken at home or in a clinic. - 02
Return
The sample is returned according to the kit instructions. - 03
Analyse
High-resolution mass spectrometry and bioinformatic analysis of the protein profile. - 04
Report
A personalised proteomic report with explanations and recommendations.
Method and evidence
Method and evidence
Analytical method
High-resolution Orbitrap mass spectrometry with data-independent acquisition (DIA), followed by bioinformatic analysis. The platform can identify up to 9,000 proteins; the routine workflow uses a curated spectral library of 7,496 protein groups. Coverage is not a guarantee that every protein is quantified in every sample.What ProteoAge represents
ProteoAge is trained to estimate chronological age from the abundance patterns of 508 proteins in buccal-swab samples. The difference from chronological age is reported as relative age acceleration or deceleration. It is a model-derived estimate, not a direct measurement of whole-body ageing or mortality risk.Repeatability
In 20 stable controls sampled about one month apart, relative biological age had a test-retest ICC of 0.905 (95% CI 0.776–0.961). A baseline study of more than 500 participants reported a sample correlation of 0.84. This supports repeatability within the studied setting; it does not establish clinical outcome prediction or a threshold for meaningful individual change.Analytical controls
Reference samples run across plates and batches. On raw, non-normalised data the median protein-level CV is 30.4%, and housekeeping proteins range from 21.4% to 29.2%. Normalisation and batch correction then reduce technical variation. Reprocessing the same raw data gives 99% overlap in the selected fragments.
Repeatability of relative biological age
Collection and analytical controls
- 0.84Correlation between two baseline samples, more than 500 participants
- 30.4%Median protein-level CV across reference samples, raw and uncorrected
- 21–29%CV of housekeeping proteins across reference samples, raw
- 99%Overlap in selected fragments when the same raw data is processed twice
Clinical value
Use in a multi-omics programme
Establish a proteomic baseline and explore changes over time alongside clinical history, routine laboratory testing and other omics results.
- 01
Baseline
Establish the proteomic profile before anything changes. - 02
Combine
Read it with clinical history, routine testing and other omics. - 03
Re-measure
Interpret change against sampling conditions, analytical variation and biological variability.
Measure → Intervene → Re-measure → Verify
White-label opportunity
Your programme. Your brand. Our infrastructure.
Advanced Proteomics can be integrated into healthcare, longevity and preventive-health programmes as a branded or co-branded testing pathway, without building the laboratory infrastructure behind it.
- Branded test kits and packaging
- Integration into existing clinic or longevity programmes
- Remote sample collection
- Laboratory analysis
- A patient-facing experience in your name
- Results delivered into your preferred reporting environment
- Repeat testing and longitudinal programmes
Remote access
Sample collection at home, outside the clinic.Functional depth
A protein-based ageing and lifestyle layer, without a blood draw.Longitudinal use
Repeat testing to follow change over time.
Limitations
A model-derived view, not a diagnosis
Buccal samples reflect oral epithelial biology and may also contain broader biological signals. Hallmark and functional scores are inferred from protein patterns: they are not direct measurements of telomere length, DNA methylation, microbiome composition, blood vitamin levels or standard serum lipid and inflammatory markers. Contributions shown in years are model outputs, not years of life gained or lost, and a lower age estimate alone does not demonstrate reversal of ageing or improved health outcomes.
For informational and wellness use. The report does not independently diagnose disease or nutrient deficiency and does not replace clinical assessment. Recommendations require review for individual suitability. Availability and regulatory status vary by market.
Contact
Thirty minutes, and you will know whether this fits your clinic.
Tell us how your clinic works today and which patients you see. We will go through the portfolio, what can be offered in your market, and what your team would need from us.