A clear glass DNA double helix with gold rungs, beside an unlabelled saliva tube and two capsules, on travertine.

Diagnostic menu


Genetics & Pharmacogenetics

One DNA test. Lifelong genetic insight.

Saliva sample, collected at home or in clinic.

  • SalivaNon-invasive collection
  • 25 genesIn the pharmacogenetic panel
  • 7 pathwaysPathway-focused gene groups

Clinical value

Clinical value for physicians

A saliva-based genetic test providing structured insight into genetic predispositions, biological pathways and medication response. It translates relevant genetic variation into structured, clinically contextualised insights.

Because inherited genetic information remains largely stable throughout life, it provides a long-term layer of information that clinicians can consider alongside medical history, phenotype, lifestyle and dynamic biomarkers.

  • 01
    • Add inherited genetic context to the patient’s broader health profile
  • 02
    • Review variants associated with drug metabolism alongside current medication and clinical factors
  • 03
    • Explore biological pathways and genetic associations that add context
  • 04
    • Combine stable genetic information with phenotype, history, lifestyle and dynamic biomarkers

What is measured

What your patient sees

A lifelong genetic profile presented across practical health domains, designed to be understood in a clinical conversation. The physician remains central to interpretation, prescribing and treatment decisions.

  • Genetic traits relevant to individual health characteristics.
  • Genetic insights that can add context to lifestyle and preventive health discussions.
  • Genetic variants associated with potential differences in medication response.
  • Genetic variants associated with selected health conditions.
  • Genetic information related to drug metabolism and selected pharmacogenetic pathways.
  • Consolidated findings, points of attention and pathway views for the clinician.

Inside the report

What the report shows

Clinician dashboard

Clinician dashboard · example patientAs expected Point of attention
Methylation
  • MTHFR
  • MTR
  • MTRR
  • BHMT
  • CBS
  • COMT
Detoxification
  • CYP1A2
  • CYP2C19
  • CYP2D6
  • GSTM1
  • NAT2
  • UGT1A1
Oxidative stress
  • SOD2
  • CAT
  • GPX1
  • NQO1
  • NOS3
Estrogen metabolism
  • CYP1B1
  • CYP19A1
  • COMT
  • SULT1A1
  • GSTP1
Consolidated genetic findings and points of attention, grouped by pathway. Illustrative example, not a patient result.

Biochemical pathway view

Folate cycleMethionine cycleTHFDHF5,10-methylene-THF5-methyl-THFMethionineSAMeSAHHomocysteineDHFRMTHFRMAT1AGNMT · PEMTAHCYMTR · MTRRCBSCystathionine5-methyl-THF donates its methyl group to homocysteine
Variants are shown in the pathway they act in. Here, the methylation and one-carbon pathway: MTHFR and MTR link the folate and methionine cycles. Highlighted genes are illustrative.

Patient report

Medication response
  • CYP2C19Intermediate metaboliser
  • CYP2D6Normal metaboliser
  • SLCO1B1Decreased function
  • VKORC1Typical sensitivity
Genetic predispositions
  • CardiovascularAverage
  • Type 2 diabetesSlightly increased
  • Alzheimer’s diseaseAverage
  • Coeliac diseaseLow
Lifestyle & traits
  • Caffeine metabolismFast
  • Lactose toleranceLikely tolerant
  • Muscle fibre typeMixed
  • Alcohol flushUnlikely
Illustrative patient view with example results. Genetic predisposition is not a diagnosis; prescribing decisions remain with the clinician.

Genes & markers included in the analysis

Pharmacogenetics

ABCG2, BCHE, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6, CYP3A4, CYP3A5, DPYD, F2, F5, HLA-A*31:01, HLA-B*15:02, HLA-B*57:01, IFNL3, MTHFR, NUDT15, PROC, PROS1, SERPINC1, SLCO1B1, TPMT, UGT1A1, VKORC1

Traits

ACTN3, ADH1B, AHSG, ALDH2, ALDOB, AR, ATP7B, AUTS2, CCL2, CYP1A2, EBF1, EDA2R, F2, F5, FGF5, FUT2, HDAC9, HFE, HLA-DQA1, HLA-DQB1, IRF4, LCT, MAPT-AS1 (SPPL2C), MBL2, MX1, OAS1, PAX1/FOXA2, PROC, PROS1, SERPINA1, SERPINC1, SLC14A2, TAS2R38, WNT10A

Health-associated genes

ABCA1, ABCA4, ABCA7, ABO, ACE, APOB, APOC3, APOE, APC, BIN1, BRCA-pathway-related markers, CDKN2A/B, CLU, FTO, GBA, GCK, GCKR, HNF1B, IL6, IL6R, KCNJ11, KCNQ1, LPA, LRRK2, MAPT, MC4R, MTHFR, MUTYH, PCSK9, PNPLA3, PPARG, TCF7L2, TERT, TP53, TREM2 and more

Pathway-focused gene groups
Methylation

MTHFR, MTR, MTHFD1, DHFR, MTRR, BHMT, MAT1A, AHCY, PEMT, GNMT, CBS, CTH, SUOX

Detoxification & drug metabolism

SLCO1B1, CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5, DPYD, NUDT15, BCHE, CYP1A1, CYP1B1, CYP2A6, CYP2C8, CYP2E1, CYP2F1, CYP4F2, ITPA, NQO1, PON1, ADH1B, ALDH2, GSTM1, GSTT1, GSTP1, GSTA1, UGT1A1, SULT1A1, SULT1E1, NAT1, NAT2, TPMT, COMT, BHMT, HNMT, PEMT, ABCB1, ABCG2, VKORC1

Oxidative stress

SOD2, CAT, GPX1, SOD3, GSTM1, GSTT1, GSTP1, GSTA1, G6PD, NOS3

Estrogen metabolism

CYP17A1, CYP19A1, SRD5A2, CYP1A1, CYP1A2, CYP1B1, CYP3A4, UGT1A1, COMT, GSTM1, GSTT1, GSTP1, GSTA1, SULT1A1, SULT1E1, NQO1, SOD2, SOD3, CAT, GPX1

Neurotransmitters

TH, QDPR, DDC, COMT, MAOA, MAOB, DRD1, DRD2, DRD3, DRD4, DBH, ALDH2, ADRB2, HTR2A, HTR1A, HTR2B, DAO, HNMT, NAT2, OXTR, OPRM1, GABRA2, GRIK4, BDNF, VDR

Vitamins & micronutrients

BCO1, TTR, NBPF3, ALPL, MTHFR, FUT2, FUT6, TCN1, TCN2, CD320, MMUT, CLYBL, SLC23A1, SLC23A2, CYP2R1, GC, VDR, CYP27B1, DHCR7, SCARB1, CYP4F2, ZPR1, APOA5, APOB, VKORC1, TRPM6, TRPM7, CLDN16, CLDN19, SLC12A3

Inflammation

IL1A, IL1B, IL6, TNF / LTA, CRP, IL17A, IL10, IL1RN, IL6R, FKBP5, APOE, FADS1

A summary of the laboratory’s gene and marker documentation. The full list includes additional health-associated genes beyond the examples shown here.

What you get

Patient value

    • Understand predispositions: clear categories for inherited tendencies to discuss with a professional
    • Medication guidance: where genetic variation may be associated with differences in medication response
    • Lifelong relevance: inherited information is stable and stays relevant over time
    • Selected pharmacogenetic genes: CYP2C19, CYP2C9, CYP2D6, CYP3A4/5, DPYD, SLCO1B1, TPMT, UGT1A1, VKORC1, NUDT15, BCHE, ABCG2
    • Pathway views: methylation, drug metabolism, oxidative stress, estrogen metabolism, neurotransmitters, vitamins, inflammation
    • Points of attention consolidated in one clinician dashboard

How it works

From saliva sample to clinical conversation

  1. 01A saliva sample with a certified collection kit, at home or in clinic.
  2. 02Genetic analysis in an ISO 15189-accredited laboratory.
  3. 03The clinician reviews findings and pathway views in the dashboard.
  4. 04Results are discussed with the patient in their clinical context.

Method and evidence

Secure. Accredited. Clinician-focused.

  • ISO 27001 certified.
  • Genetic analyses are conducted in an ISO 15189-accredited laboratory.
  • Saliva is collected with kits manufactured under an ISO 13485-certified quality management system.

Clinical value

How to use the results clinically

Genetic results should always be interpreted in clinical context.

  1. 01Interpret inherited variants alongside medical history, phenotype, family history, current medication and relevant biomarkers.
  2. 02Genetic predisposition is not a diagnosis. Discuss associations and uncertainty within the patient’s broader clinical context.
  3. 03Focus the consultation on findings that may provide useful context for prevention, medication response or follow-up.

Measure → Intervene → Re-measure → Verify

White-label opportunity

Your programme. Your brand. Our infrastructure.

Genetics & Pharmacogenetics can be integrated into healthcare, longevity and preventive-health programmes as a branded or co-branded testing pathway, without building the laboratory infrastructure behind it.

  • Branded test kits and packaging
  • Integration into existing clinic or longevity programmes
  • Remote sample collection
  • Laboratory analysis
  • A patient-facing experience in your name
  • Results delivered into your preferred reporting environment
  • Repeat testing and longitudinal programmes
  • Sample collection at home, outside the clinic.
  • Stable genetic context and medication-response insight from one saliva sample.
  • Repeat testing to follow change over time.

Limitations

Clinical note

Pharmacogenetic information is intended to provide additional genetic context and should not replace professional judgement, current prescribing guidance or relevant patient-specific factors. Genetic predisposition is not a diagnosis.

Genetic associations should be considered alongside medical history, family history, phenotype, lifestyle and other relevant clinical information. The physician remains central to interpretation and all treatment-related decisions. Availability and regulatory status vary by market.

Download fact sheet (PDF)Back to the diagnostic menu

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