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Metabolic Resilience
One blood sample. A deeper view of metabolic health and future disease risk.
Finger-prick blood sample, collected at home or in clinic.
- ~30established blood markers in the base analysis
- 108metabolic biomarkers with the metabolomics add-on
- 1dried blood sample for the test and both add-ons
Why
Metabolic health takes more than standard blood markers
Blood-based metabolomic profiling that combines molecular biomarkers with structured risk assessment and metabolic-health insights in a single analysis.
Standard blood tests give a valuable snapshot, but metabolic biology has many dimensions. Metabolic Resilience combines detailed molecular measurements with risk and metabolic-health outputs, for a broader picture of metabolic physiology today and health risk ahead.
- 01
10-year chronic-disease risk
- Heart attack
- Cardiovascular disease
- Type 2 diabetes
- Liver fibrosis and cirrhosis
- Chronic kidney disease
- Alcohol-related liver disease
- COPD
- Lung cancer
- 02
Metabolic health
- Metabolic Age
- Metabolic Resilience Score
- Lipid metabolism
- Fatty acid balance
- Glucose metabolism
- Amino acid metabolism
- Chronic inflammation
- 03
Molecular biomarkers
- Lipids & lipoproteins
- Apolipoproteins
- Fatty acids
- Amino acids
- Glucose metabolism
- Inflammation (GlycA)
- Organ-related markers
What is measured
One sample. Many dimensions of metabolic biology.
The base analysis includes around 30 established blood markers of clinical quality, from one self-collected dried blood sample. The same sample can be extended with the add-ons below.
Lipids & lipoproteins
LDL-C, HDL-C, total cholesterol, VLDL-C, total triglycerides, ApoB, ApoA1 and the ApoB/ApoA1 ratio.Fatty acids
Total fatty acids, and omega-3, omega-6, DHA, MUFA, PUFA, SFA and linoleic acid as a percentage of the total.Amino acids
Branched-chain amino acids, alanine, glycine, histidine, isoleucine, leucine, tyrosine and valine.Glucose metabolism
Glucose and related metabolic signals.Inflammation
GlycA, an inflammation-related metabolic marker.Organ-related markers
Creatinine, eGFR and albumin.
Add-ons
Two add-ons, measured on the same sample
One dried blood sample can give up to three layers of insight: the Metabolic Resilience analysis, plus one or two optional add-ons. No extra sample, clinic visit or venous blood draw is needed.
- Add-on 1 · Metabolomics
Extended metabolomics panel
Extends the analysis to 108 metabolic biomarkers from the same dried blood sample: lipids, lipoproteins, fatty acids, amino acids, ketone bodies, inflammation and fluid balance. Available only together with Metabolic Resilience.- 108 biomarkers in 16 categories
- Cholesterol, total lipids and triglycerides across 14 lipoprotein subclasses
- Fatty-acid ratios, amino acids, ketone bodies and GlycA
- HbA1c available as an extra service
- Add-on 2 · Proteomics
Neuro protein panel
A proteomics panel for brain health and neurodegeneration research, measured on the same dried blood sample. It adds a protein layer on top of the metabolic data.- Alzheimer’s disease research, built on core central nervous system (CNS) biomarkers
- Broad coverage of tau isoforms: 12 assays across brain-derived and peripheral measures
- In-depth protein profiling for Parkinson’s disease research
- Markers studied in non-Alzheimer dementias, ALS, multiple sclerosis, glioma and brain injury
- Molecular links between vascular health and brain health
- Very high analytical sensitivity, with a high detection rate also in people without symptoms
- Optional, with or without the metabolomics panel
The neuro protein panel does not diagnose, predict or exclude Alzheimer’s disease, Parkinson’s disease, dementia or any other neurological condition.
All 108 biomarkers in the extended metabolomics panel
| Category | Biomarkers | Number | Unit |
|---|---|---|---|
| Lipoprotein subclasses | Cholesterol, total lipids and triglycerides in 14 subclasses: VLDL (5), IDL, LDL (3), HDL (4) | 42 | mmol/L |
| Fatty acids | Total, degree of unsaturation, omega-3, omega-6, PUFA, MUFA, SFA, linoleic acid, DHA | 9 | mmol/L, degree |
| Fatty-acid ratios | Omega-3, omega-6, PUFA, MUFA, SFA, LA and DHA as % of total; PUFA/MUFA; omega-6/omega-3 | 9 | %, ratio |
| Cholesterol | Total, non-HDL, remnant, VLDL, clinical LDL, LDL, HDL | 7 | mmol/L |
| Amino acids | Alanine; total BCAA, isoleucine, leucine, valine; tyrosine | 6 | mmol/L |
| Other lipids | Phosphoglycerides, TG/phosphoglyceride ratio, total cholines, phosphatidylcholines, sphingomyelins | 5 | mmol/L, ratio |
| Triglycerides | Total; in VLDL, LDL, HDL | 4 | mmol/L |
| Phospholipids | Total in lipoprotein particles; in VLDL, LDL, HDL | 4 | mmol/L |
| Cholesteryl esters | Total esterified cholesterol; in VLDL, LDL, HDL | 4 | mmol/L |
| Free cholesterol | Total; in VLDL, LDL, HDL | 4 | mmol/L |
| Total lipids | In lipoprotein particles; in VLDL, LDL, HDL | 4 | mmol/L |
| Lipoprotein particle concentrations | Total; VLDL, LDL and HDL particles | 4 | mmol/L |
| Apolipoproteins | ApoB, ApoA1, ApoB/ApoA1 | 3 | g/L, ratio |
| Ketone bodies | 3-hydroxybutyrate | 1 | mmol/L |
| Fluid balance | Creatinine | 1 | µmol/L |
| Inflammation | Glycoprotein acetyls (GlycA) | 1 | mmol/L |
| Total | 108 |
What you get
From molecular data to a clearer metabolic picture
For the patient
- 10-year risk estimates for eight chronic diseases, as low, elevated or high, taking age and sex into account
- Metabolic Age
- Metabolic Resilience Score
- A detailed metabolic biomarker profile
- A baseline to return to over time
For the clinician
- Broader metabolic context than isolated markers
- Structured risk information to support follow-up
- Detailed lipid, fatty-acid, amino-acid and inflammatory data
- Optional add-ons for deeper metabolomic and brain-focused protein data from the same sample
- Data to read alongside history, lifestyle and other findings
- A basis for longitudinal reassessment
How it works
A simple remote workflow, from sample to insight
- 01
Collect
A small finger-prick blood sample, taken with the collection kit at home or in clinic. The dried sample keeps for up to three weeks, more than 95 % of samples are analysed successfully in real-world use, and one sample covers the add-ons too. - 02
Analyse
The laboratory measures the sample with high-throughput NMR spectroscopy, many blood markers in one analysis. - 03
Model
An algorithm turns the spectrum into blood markers used in clinical practice, which are combined with metabolic-health and risk models. - 04
Review
Results are returned for interpretation and appropriate follow-up.
Video
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Method and evidence
The technology behind the analysis
Many markers, one sample
Instead of testing one marker at a time, the laboratory measures many blood markers from one sample with NMR spectroscopy. The markers are linked with a large dataset of health outcomes, which makes it possible to estimate disease risk for several chronic diseases at once.Use in research
As documented by the laboratory, the technology is used by more than 200 medical research organisations in more than 30 countries, has been applied to more than two million samples and is supported by more than 900 peer-reviewed publications.Population cohorts
The extended metabolomics panel is the same NMR-based panel the laboratory has measured in large research cohorts such as UK Biobank (500,000 samples) and the Copenhagen General Population Study.
Clinical value
From measurement to meaningful follow-up
Metabolic Resilience adds a dynamic metabolic layer to preventive-health and longevity programmes. The value lies not only in the number of biomarkers, but in combining molecular detail, risk context and repeat measurement.
- 01
Identify
Find metabolic patterns and areas of increased risk. - 02
Intervene
Use the wider clinical picture to personalise the next steps. - 03
Re-measure
Track relevant metabolic change over time.
Measure → Intervene → Re-measure → Verify
White-label opportunity
Your programme. Your brand. Our infrastructure.
Metabolic Resilience can be integrated into healthcare, longevity and preventive-health programmes as a branded or co-branded testing pathway, without building the laboratory infrastructure behind it.
- Branded test kits and packaging
- Integration into existing clinic or longevity programmes
- Remote sample collection
- Laboratory analysis
- A patient-facing experience in your name
- Results delivered into your preferred reporting environment
- Repeat testing and longitudinal programmes
Remote access
Sample collection at home, outside the clinic.Metabolic depth
Molecular profiling and risk context added to the patient journey.Longitudinal use
Repeat testing to follow change over time.
Limitations
Risk assessment is not diagnosis
A risk estimate does not mean that a person has, or will develop, a particular disease. Results should be read within the wider clinical context: medical history, symptoms, lifestyle, physical findings and other relevant investigations.
Metabolic Resilience supports, and does not replace, clinical assessment. Availability, intended use and regulatory status vary by market and may differ between the base test and the add-ons. Definitions and validation of Metabolic Age, the Metabolic Resilience Score and the risk outputs follow the applicable product documentation.
Contact
Thirty minutes, and you will know whether this fits your clinic.
Tell us how your clinic works today and which patients you see. We will go through the portfolio, what can be offered in your market, and what your team would need from us.